Origins of Glyco-Gen


In 2004 Dr. Untisz's Kelpie, Dodge, developed a potentially life threatening condition called Exertional Rhabdomyolysis, or "Tying Up". An alarming set of symptoms developed including collapsing while training. His body was breaking down muscle tissue to try to generate the energy source it so desperately needed. Dr. Untisz knew she would have to find a solution before her talented partner literally worked himself to death.

With nutrition research in hand she delved further into the world of canine athletics. Using sled dogs as a model for her research she opened gateways to information resulting in Glyco-Gen, the product that gave Dodge the energy he needed to continue his competitive career.



Energy and the Working Dog

Angie Untisz DVM

Working dogs are truly premier canine athletes.  As such, one should pay close attention to
meeting their energy needs.  There are 3 sources of energy… fats, carbohydrates and proteins.  
Understanding how the working dog utilizes energy and how best to balance these energy
stores can result in a more responsive partner that is less prone to physical injury.

Fats are the most energy dense of all the sources providing 70-90% of the energy needed for
muscle contraction (primarily fueling slow twitch fibers).  In the working dog, 50-65% of
total energy in a diet should come from fats.  (This translates to 25-32.5% fat on a dry matter
basis.)  When fed a high fat diet, the working dog will develop pathways that promote
aerobic oxidation of free fatty acids (fat adaptation).  In addition, adding an anti-oxidant
such as Vitamin E and the amino acid l-carnitine can improve the muscle’s use of fat.  
Aerobic oxidation of free fatty acids leads to less lactic acid build up in the muscle and better

Carbohydrates are stored in muscle as glycogen.  Muscle uses glycogen during the initial
moments of activity and for bursts of speed and power (primarily fueling fast twitch fibers).  
Glycogen stores are relatively small and can be rapidly depleted leading to muscle weakness
and fatigue.  However, diets high in carbohydrates can lead to deconditioning (poor
endurance, obesity, muscle injury).  For a working dog, carbohydrates should be limited to
10-15% of the total energy in the diet.  To improve the working dog’s use of carbohydrates,
one should focus on replenishing glycogen stores and slowing glycogen depletion.  

Replenishing glycogen stores is accomplished by providing a “good carbohydrate” at an
appropriate time.  Muscle cells have GLUT4 pathways that are active during exercise and for
up to 30 minutes after exercise.  These pathways allow for the uptake of carbohydrate into the
muscle without the release of insulin.    Simple sugars (glucose, dextrose, fructose, corn
syrup) cause an insulin release that leads to subsequent hypoglycemia (low blood sugar).  
Complex starches (bread, rice, grains) take too long to be digested and absorbed.  Both cause
fluid imbalances that can contribute to diarrhea and dehydration.  Maltodextrin is a small
complex carbohydrate and is the ideal carbohydrate for this purpose.  Maltodextrin is rapidly
absorbed without an insulin release or fluid imbalance and is readily utilized by the GLUT4
pathway.  When a maltodextrin supplement is given within 30 minutes of exercise, up to 85%
of pre-exercise glycogen levels are restored.  Without this targeted approach, only 40% of pre-
exercise levels are restored.

Slowing depletion of glycogen stores is accomplished in two ways.  First, when enough fat is
fed, slow twitch fibers will use free fatty acids as their energy source (fat adaptation) sparing
glycogen for use by fast twitch fibers.  Second, supplementing prior to activity with a “good
carbohydrate” such as maltodextrin will give the working dog a little carbohydrate “to burn”
before starting on the glycogen stores.  It is very important to avoid simple sugars and
starches to avoid insulin spikes and fluid imbalances.

Proteins are the building blocks of muscle and should not be a major source of energy.  
Animal source proteins (chicken, beef, lamb, egg, etc.) are preferred and often offer increased
digestibility with a good amino acid balance.  Diets low in protein have been associated with
increased injuries.  A working dog diet should have a minimum 26% protein.  For hard
working dogs, diets containing 30-40% protein are even better.  The goal is to spare the use of
protein as an energy source so it can be used to build muscle mass and repair muscle

In summary, working dogs should be fed a diet high in fat to optimize energy availability
and high in protein to protect against injury.  Carbohydrates should be supplemented at
appropriate times to improve their storage.  Remember, feed for energy and you will have
energetic dogs.